Canadian Medical Guide > Chemicals and Drugs > Immunologic and Biological Factors > Biological Products > Vaccines > Vaccines, Subunit Terms and Definitions

Vaccines, Subunit

Medical Definition:	Vaccines consisting of one or more antigens that stimulate a strong immune response. They are purified from microorganisms or produced by recombinant DNA techniques, or they can be chemically synthesized peptides.
Guide Notes:	IM general only; coord NIM with specific vaccine (IM)
Also Called:	Vaccines, Peptide
Previously Indexed:	Vaccines, Synthetic (1978-2000)

Vaccines, Subunit Categories.

	ISCOMs - A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines.
	Vaccines, Acellular - Vaccines that are produced by using only the antigenic part of the disease causing organism. They often require a "booster" every few years to maintain their effectiveness.

Vaccines, Subunit Medical Definitions and Terms

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