Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Alkaloids > Tropanes > Cocaine Terms and Definitions




Cocaine

Medical Definition: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Guide Notes: cocaine derivatives = COCAINE /analogs;CRACK COCAINE is available; cocaine addiction = COCAINE-RELATED DISORDERS
Also Called: Cocaine Hydrochloride
CAS Type 1 Name: CAS Number: 50-36-2
Cocaine Categories.
Canadian Medical Guide Definition Crack Cocaine - The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.

Cocaine Medical Definitions and Terms

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