Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Transcription Factor AP-1 Terms and Definitions

Transcription Factor AP-1

Medical Definition:	A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
Guide Notes:	in genetic transcription; /biosyn /physiol permitted; DF: AP 1
Previously Indexed:	Proto-Oncogene Proteins c-jun (1992-1994),Transcription Factors (1988-1994)

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