Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Tissue Inhibitor of Metalloproteinases > Tissue Inhibitor of-Metalloproteinase-3 Terms and Definitions

Tissue Inhibitor of-Metalloproteinase-3

Medical Definition:	A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21 kD, nonglycosylated protein. TIMP-3 does not show a high degree of structural similarity unlike TIMP-1 and TIMP-2 which are structurally similar. However, it does possess a high degree of structural similarity with that of chicken TIMP-3 (ChIMP-3). Human TIMP-3 is of particular concern because of its potential role in cancer, arthritis, and eye diseases.
Guide Notes:	DF: note short X ref
Also Called:	Chicken Inhibitor of Metalloproteinases-3
Previously Indexed:	Neoplasm Proteins (1992-1995),Proteins (1995-1997)

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