Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Thiazoles > Thiadiazoles Terms and Definitions




Thiadiazoles

Medical Definition:
Guide Notes: includes thiadiazolines, thiadiazolidines
Previously Indexed: Heterocyclic Compounds (1966-1970)
Thiadiazoles Categories.
Canadian Medical Guide Definition Acetazolamide - One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Canadian Medical Guide Definition Methazolamide - A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.

Thiadiazoles Medical Definitions and Terms

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