Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Serpins > Plasminogen Inactivators Terms and Definitions




Plasminogen Inactivators

Medical Definition: Important modulators of the activity of plasminogen activators. Four inhibitors, all belonging to the serpin family of proteins, have been implicated in plasminogen activation inhibition. They are PAI-1, PAI-2, protease-nexin, and PROTEIN C INHIBITOR; (PAI-3). All inhibit both the tissue-type and urokinase-type plasminogen activators.
Guide Notes: serpins; DF: PLASMINOGEN INACT
Also Called: Plasminogen Activator Inhibitors, Endothelial,BAE-PAI,Plasminogen Activator Inhibitors, Placental
Previously Indexed: Glycoproteins (1966-1989),Plasminogen Activators/antagonists & inhibitors (1976-1989)
Plasminogen Inactivators Categories.
Canadian Medical Guide Definition Protein C Inhibitor - A member of the serpin family of proteins that is found in plasma and urine. It is dependent on heparin and able to inhibit activated protein C, thrombin, kallikrein, and other SERINE ENDOPEPTIDASES.

Plasminogen Inactivators Medical Definitions and Terms

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