Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds with 4 or More Rings > Rifamycins > Rifampin Terms and Definitions

Rifampin

Medical Definition:	A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
Also Called:	Tubocin,Rimactan,Rifadin,Rimactane
CAS Type 1 Name:	CAS Number:	13292-46-1
Previously Indexed:	Rifamycins (1966-1972)

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