Canadian Medical Guide > Biological Sciences > Biological Phenomena, Cell Phenomena, and Immunity > Biological Phenomena > Regeneration > Bone Remodeling Terms and Definitions

Bone Remodeling

Medical Definition:	The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Guide Notes:	note category: an aspect of bone physiol
Previously Indexed:	Bone Development (1967-1991),Bone Regeneration (1967-1991),Bone Resorption (1967-1991)

Bone Remodeling Categories.

Bone Regeneration - Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after bone fracture but not yet replaced by hard bone.

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