Canadian Medical Guide > Chemicals and Drugs > Enzymes and Coenzymes > Enzymes > Recombinases > Integrases Terms and Definitions
Integrases
Medical Definition: | Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA. |
Guide Notes: | HIV INTEGRASE is also available |
CAS Number: | EC 2.7.7.- |
Previously Indexed: | Coliphages/enzymology (1974-1980),DNA Helicases (1974-1987),DNA Nucleotidyltransferases (1974-1996),Viral Proteins (1980-1987) |
Transposases - Enzymes that recombine DNA segments by a process which involves the formation of a synapse between two DNA helices, the cleavage of single strands from each DNA helix and the ligation of a DNA strand from one DNA helix to the other. The resulting DNA structure is called a HOLLIDAY JUNCTION which can be resolved by DNA REPLICATION or by HOLLIDAY JUNCTION RESOLVASES. |
Integrases Medical Definitions and Terms
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