Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 2-Ring > Quinazolines > Trimetrexate Terms and Definitions
Trimetrexate
| Medical Definition: | A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect. | |
| Also Called: | CI-898,JB-11,NSC-249008,NSC-328564,Trimetrexate Hydrate,Trimetrexate Monohydrate, Monoacetate | |
| CAS Type 1 Name: | CAS Number: | 52128-35-5 |
| Previously Indexed: | Antineoplastic Agents (1966-1991),Folic Acid Antagonists (1966-1991),Quinazolines (1966-1991) |
Trimetrexate Medical Definitions and Terms
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