| Medical Definition: |
Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES). |
| Guide Notes: |
prion proteins; PrPSc stands for PRion Protein SCrapie; do not confuse with PRPC PROTEINS; /pathogen permitted; DF: PRPSC |
| Also Called: |
Scrapie Agent,Scrapie HaSp33-37 Protein,PrP (CJD),PrP (GSS) |
| Previously Indexed: |
Prions (1992-1994),Viral Proteins (1989-1991) |
CANADIAN
MEDICAL GUIDE