Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Prions > PrPSc Proteins Terms and Definitions




PrPSc Proteins

Medical Definition: Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
Guide Notes: prion proteins; PrPSc stands for PRion Protein SCrapie; do not confuse with PRPC PROTEINS; /pathogen permitted; DF: PRPSC
Also Called: Scrapie Agent,Scrapie HaSp33-37 Protein,PrP (CJD),PrP (GSS)
Previously Indexed: Prions (1992-1994),Viral Proteins (1989-1991)
PrPSc Proteins Categories.
Canadian Medical Guide Definition PrP 27-30 Protein - Protease-resistant core of PrPSC, the abnormal isoform of prion proteins (PRIONS). PrP 27-30 is produced by limited proteolysis of the N-terminus of PrPSc.

PrPSc Proteins Medical Definitions and Terms

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