Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Prions > PrPC Proteins Terms and Definitions
PrPC Proteins
Medical Definition: | Normal cellular isoform of prion proteins (PRIONS) encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity. |
Guide Notes: | PrPC stands for PRion Protein Cellular; do not confuse with PRPSC PROTEINS which are scrapie prions; /pathogen permitted; DF: PRPC |
Previously Indexed: | Prions (1992-1994) |
PrPC Proteins Medical Definitions and Terms
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