Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Prions > PrPC Proteins Terms and Definitions




PrPC Proteins

Medical Definition: Normal cellular isoform of prion proteins (PRIONS) encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.
Guide Notes: PrPC stands for PRion Protein Cellular; do not confuse with PRPSC PROTEINS which are scrapie prions; /pathogen permitted; DF: PRPC
Previously Indexed: Prions (1992-1994)

PrPC Proteins Medical Definitions and Terms

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