Canadian Medical Guide > Chemicals and Drugs > Carbohydrates and Hypoglycemic Agents > Carbohydrates > Polysaccharides > Proteoglycans Terms and Definitions
Proteoglycans
Medical Definition: | Glycoproteins which have a very high polysaccharide content. |
Guide Notes: | polysaccharides |
Also Called: | Proteoglycan Type H |
Previously Indexed: | Mucopolysaccharides (1966-1974) |
Platelet Factor 4 - A high-molecular-weight proteoglycan-platelet factor complex which is released from blood platelets by thrombin. It acts as a mediator in the heparin-neutralizing capacity of the blood and plays a role in platelet aggregation. At high ionic strength (I=0.75), the complex dissociates into the active component (molecular weight 29,000) and the proteoglycan carrier (chondroitin 4-sulfate, molecular weight 350,000). The molecule exists in the form of a dimer consisting of 8 moles of platelet factor 4 and 2 moles of proteoglycan. | |
Proteochondroitin Sulfates - Proteoglycans found in cartilage. They consist of several chondroitin sulfate molecules linked to protein(s) by neutral sugar linkage regions. |
Proteoglycans Medical Definitions and Terms
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