Canadian Medical Guide > Biological Sciences > Genetic Phenomena > Variation (Genetics) > Polymorphism (Genetics) > Polymorphism, Single-Stranded Conformational Terms and Definitions




Polymorphism, Single-Stranded Conformational

Medical Definition: Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Guide Notes: POLYMORPHISM, SINGLE NUCLEOTIDE is also available
Previously Indexed: Polymorphism (Genetics) (1990-1994)

Polymorphism, Single-Stranded Conformational Medical Definitions and Terms

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