Canadian Medical Guide > Diseases > Nervous System Diseases > Neuromuscular Diseases > Peripheral Nervous System Diseases > Pain Insensitivity, Congenital Terms and Definitions

Pain Insensitivity, Congenital

Medical Definition:	A syndrome characterized by indifference to PAIN despite the ability to distinguish noxious from nonnoxious stimuli. Absent corneal reflexes and MENTAL RETARDATION may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343)
Guide Notes:	congenital insensitivity to pain with anhidrosis = HSAN IV see NEUROPATHIES, HEREDITARY SENSORY AND AUTONOMIC; DF: PAIN INSENSITIVITY CONGEN

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