Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Peptides > Tyrothricin Terms and Definitions

Tyrothricin

Medical Definition:	A polypeptide antibiotic mixture obtained from Bacillus brevis. It consists of a mixture of three tyrocidines (60%) and several gramicidins (20%) and is very toxic to blood, liver, kidneys, meninges, and the olfactory apparatus. It is used topically.
Also Called:	Dermotricine,Hydrotricine,Martricin,Tyroderm
CAS Type 1 Name:	CAS Number:	1404-88-2

Tyrothricin Categories.

	Gramicidin - A group of PEPTIDE ANTIBIOTICS from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN which is used topically for gram-positive organisms. It is toxic to blood, liver, kidneys, meninges, and the olfactory apparatus.
	Tyrocidine - An antibiotic mixture produced by Bacillus brevis which may be separated into three components, tyrocidines A, B, and C. It is the major constituent (40-60 per cent) of tyrothricin, gramicidin accounting for the remaining 10-20 per cent active material. It is a topical antimicrobial agent, that is very toxic parenterally.

Tyrothricin Medical Definitions and Terms

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