Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Peptides > Peptides, Cyclic > Cyclosporins Terms and Definitions




Cyclosporins

Medical Definition: A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
Guide Notes: immunosuppressants; do not confuse with CYCLOSPORINE, a specific drug, or its X ref CYCLOSPORIN
Previously Indexed: Immunosuppressive Agents (1966-1981),Peptides (1966-1970),Peptides, Cyclic (1971-1981)
Cyclosporins Categories.
Canadian Medical Guide Definition Cyclosporine - A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).

Cyclosporins Medical Definitions and Terms

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