Canadian Medical Guide > Diseases > Pathological Conditions, Signs and Symptoms > Pathologic Processes > Necrosis Terms and Definitions

Necrosis

Medical Definition:	A pathological process caused by the progressive degradative action of enzymes that is generally associated with severe cellular trauma. It is characterized by mitochondrial swelling, nuclear flocculation, uncontrolled cell lysis, and ultimately CELL DEATH.
Guide Notes:	IM for general or for necrotic process; NIM as coord for /pathol, with no qualif; bone necrosis = OSTEONECROSIS or OSTEORADIONECROSIS; DENTAL PULP NECROSIS; FEMUR HEAD NECROSIS; KIDNEY CORTEX NECROSIS; KIDNEY PAPILLARY NECROSIS & KIDNEY TUBULAR NECROSIS,

Necrosis Categories.

	Fat Necrosis - A condition in which the death of adipose tissue results in neutral fats being split into fatty acids and glycerol.
	Gangrene - Death and putrefaction of tissue usually due to a loss of blood supply.
	Infarction - A pathological process consisting of a sudden insufficient blood supply to an area, which results in necrosis of that area. It is usually caused by a thrombus, an embolus, or a vascular torsion.

Necrosis Medical Definitions and Terms

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