Canadian Medical Guide > Chemicals and Drugs > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Amine Oxidoreductases Terms and Definitions




Amine Oxidoreductases

Medical Definition: Enzymes catalyzing the dehydrogenation of secondary amines, introducing a C=N double bond as the primary reaction. In some cases this is later hydrolyzed.
CAS Number: EC 1.5.
Previously Indexed: Oxidoreductases (1966-1974)
Amine Oxidoreductases Categories.
Canadian Medical Guide Definition Methylenetetrahydrofolate Reductase (NADPH2) - A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-METHYLTETRAHYDROFOLATE to 5,10-METHYLENETETRAHYDROFOLATE. This enzyme was formerly classified as EC 1.1.1.171.
Canadian Medical Guide Definition Oxidoreductases, N-Demethylating
Canadian Medical Guide Definition Proline Oxidase - The first enzyme of the proline degradative pathway. It catalyzes the oxidation of proline to pyrroline-5-carboxylic acid in the presence of oxygen and water. The action is not reversible. The specific activity of proline oxidase increases with age. EC 1.5.3.-.
Canadian Medical Guide Definition Pyridoxaminephosphate Oxidase - An enzyme catalyzing the deamination of pyridoxaminephosphate to pyridoxal phosphate. It is a flavoprotein that also oxidizes pyridoxine-5-phosphate and pyridoxine. EC 1.4.3.5.
Canadian Medical Guide Definition Pyrroline Carboxylate Reductases - A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.
Canadian Medical Guide Definition Saccharopine Dehydrogenases - A collection of enzymes that use either NAD+ (EC 1.5.1.7) or NADP+ (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD+ (EC 1.5.1.9) or NADP+ (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS. EC 1.5.1.
Canadian Medical Guide Definition Tetrahydrofolate Dehydrogenase - An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC 1.5.1.3.

Amine Oxidoreductases Medical Definitions and Terms

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