Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Peptides > Oligopeptides > Amanitins Terms and Definitions

Amanitins

Medical Definition:	Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis. These peptides are important in the study of transcription. Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals.
Guide Notes:	/antag permitted but consider also ANTITOXINS
Also Called:	Alpha-Amanitin,Alpha-Amanitine
Previously Indexed:	Mycotoxins (1974),Oligopeptides (1974),Peptides, Cyclic (1974)

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