Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Nitro Compounds > Nitroimidazoles Terms and Definitions

Nitroimidazoles

Medical Definition:

Nitroimidazoles Categories.

	Dimetridazole - A compound used to treat histomoniasis in poultry.
	Etanidazole - A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
	Ipronidazole - An antihistomonal agent with low toxicity. It also promotes growth and feed utilization in poultry.
	Metronidazole - An antiprotozoal used in amebiasis, trichomoniasis, giardiasis, and as a treponemacide in livestock. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
	Misonidazole - A nitroimidazole that sensitizes normally radio-resistant hypoxic cells to radiation. It may also be directly cytotoxic to hypoxic cells and has been proposed as an antineoplastic.
	Nimorazole - An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
	Ornidazole - A nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.
	Ronidazole - Antiprotozoal and antimicrobial agent used mainly in veterinary practice.
	Tinidazole - A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.

Nitroimidazoles Medical Definitions and Terms

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