Canadian Medical Guide > Diseases > Nervous System Diseases > Neurotoxicity Syndromes > Heavy Metal Poisoning, Nervous System Terms and Definitions




Heavy Metal Poisoning, Nervous System

Medical Definition: Conditions associated with damage or dysfunction of the nervous system caused by exposure to heavy metals, which may cause a variety of central, peripheral, or autonomic nervous system injuries.
Guide Notes: GEN: prefer specifics
Previously Indexed: Metals or specifics/poisoning (1966-1999),Metals, Heavy/poisoning (1997-1999)
Heavy Metal Poisoning, Nervous System Categories.
Canadian Medical Guide Definition Arsenic Poisoning - Disorders associated with acute or chronic exposure to compounds containing ARSENIC (ARSENICALS) which may be fatal. Acute oral ingestion is associated with gastrointestinal symptoms and an encephalopathy which may manifest as SEIZURES, mental status changes, and COMA. Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. (Adams et al., Principles of Neurology, 6th ed, p1212)
Canadian Medical Guide Definition Lead Poisoning, Nervous System - Injury to the nervous system secondary to exposure to lead compounds. Two distinct clinical patterns occur in children (LEAD POISONING, CHILDHOOD) and adults (LEAD POISONING, ADULT). In children, lead poisoning typically produces an encephalopathy. In adults, exposure to toxic levels of lead is associated with a peripheral neuropathy.
Canadian Medical Guide Definition Manganese Poisoning - Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include CONFUSION; HALLUCINATIONS; and an extrapyramidal syndrome (PARKINSON DISEASE, SECONDARY) that includes rigidity; DYSTONIA; retropulsion; and TREMOR. (Adams, Principles of Neurology, 6th ed, p1213)
Canadian Medical Guide Definition Mercury Poisoning, Nervous System - Neurologic disorders associated with exposure to inorganic and organic forms of MERCURY. Acute intoxication may be associated with gastrointestinal disturbances, mental status changes, and PARAPARESIS. Chronic exposure to inorganic mercury usually occurs in industrial workers, and manifests as mental confusion, prominent behavioral changes (including psychosis), DYSKINESIAS, and NEURITIS. Alkyl mercury poisoning may occur through ingestion of contaminated seafood or grain, and its characteristic features include POLYNEUROPATHY; ATAXIA; vision loss; NYSTAGMUS; and DEAFNESS. (From Joynt, Clinical Neurology, 1997, Ch20, pp10-15)

Heavy Metal Poisoning, Nervous System Medical Definitions and Terms

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