Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Peptides > Neuropeptides > Calcitonin Gene-Related Peptide Terms and Definitions

Calcitonin Gene-Related Peptide

Medical Definition:	Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Guide Notes:	a neurotransmitter; /biosyn /physiol permitted; DF: CGRP
Also Called:	alpha-CGRP,beta-CGRP,Calcitonin Gene-Related Peptide I,Calcitonin Gene-Related Peptide II
CAS Type 1 Name:	CAS Number:	83652-28-2
Previously Indexed:	Nerve Tissue Proteins (1966-1986),Neuropeptides (1987-1989)

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