Canadian Medical Guide > Biological Sciences > Musculoskeletal, Neural, and Ocular Physiology > Nervous System Physiology > Neuronal Plasticity > Long-Term Depression (Physiology) Terms and Definitions

Long-Term Depression (Physiology)

Medical Definition:	A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
Guide Notes:	note category: do not confuse with clinical DEPRESSION or DEPRESSIVE DISORDERS
Also Called:	Depotentiation
Previously Indexed:	Neuronal Plasticity (1985-2002)

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