Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Synapsins Terms and Definitions

Synapsins

Medical Definition:	A family of synaptic vesicle-associated proteins involved in the short-term regulation of neurotransmitter release. Synapsin I (Protein I), the predominant member of this family, links synaptic vesicles to actin filaments in the presynaptic nerve terminal. These interactions are modulated by the reversible phosphorylation of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and calcium-calmodulin-dependent protein kinases. It is believed that these functional properties are also shared by synapsin II (Protein III).
Guide Notes:	nerve tissue proteins; /biosyn /drug eff /physiol /ultrastruct permitted
Also Called:	Protein III,Synapsin I,Synapsin II
Previously Indexed:	Nerve Tissue Proteins (1966-1991),Neuropeptides (1987-1991),Phosphoproteins (1970-1991)

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