Canadian Medical Guide > Diseases > Neoplasms > Precancerous Conditions Terms and Definitions

Precancerous Conditions

Medical Definition:	Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Guide Notes:	IM; do not use /compl for develop into cancer: use /pathol; coord IM with organ/neopl term (IM); Manual 24.4.1.13
Also Called:	Condition, Preneoplastic

Precancerous Conditions Categories.

	Cervix Dysplasia - A spectrum of histologic changes in the epithelium of the cervix uteri which may begin as a superficial lesion and progress to invasive carcinoma.
	Erythroplasia - A condition of the mucous membrane characterized by erythematous papular lesions. (Dorland, 27th ed)
	Leukoplakia - A white patch on a mucous membrane that will not rub off. (Dorland, 27th ed)
	Lymphomatoid Granulomatosis - An angiocentric and angiodestructive lymphoreticular proliferative disorder primarily involving the lungs. Histologically it simulates malignant lymphoma and in some cases may progress to lymphoma.
	Lymphomatoid Papulosis - Clinically benign, histologically malignant, recurrent cutaneous eruption characterized by an infiltration of large atypical cells surrounded by inflammatory cells. The atypical cells resemble Reed-Sternberg cells of Hodgkin's disease or the malignant cells of cutaneous T-cell lymphoma. In some cases, lymphomatoid papulosis progresses to lymphomatous conditions including mycosis fungoides, Hodgkin's disease, cutaneous T-cell lymphoma, or Ki-1 lymphoma.
	Preleukemia - Conditions in which the abnormalities in the peripheral blood or bone marrow represent the early manifestations of acute leukemia, but in which the changes are not of sufficient magnitude or specificity to permit a diagnosis of acute leukemia by the usual clinical criteria.
	Xeroderma Pigmentosum - A rare, pigmentary, and atrophic autosomal recessive disease affecting all races. It is manifested as an extreme photosensitivity to ultraviolet light as the result of a deficiency in the enzyme that permits excisional repair of ultraviolet-damaged DNA.

Precancerous Conditions Medical Definitions and Terms

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