Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Connective and Soft Tissue > Neoplasms, Connective Tissue > Mastocytosis Terms and Definitions

Mastocytosis

Medical Definition:	A heterogenous group of disorders characterized by the abnormal increase of MAST CELLS in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMAS).
Guide Notes:	GEN or unspecified; prefer specifics
Previously Indexed:	Urticaria Pigmentosa (1966-1986)

Mastocytosis Categories.

	Mastocytoma - A solid tumor consisting of a dense infiltration of MAST CELLS. It is generally benign.
	Mastocytosis, Cutaneous - Skin lesions due to abnormal infiltration of MAST CELLS. Cutaneous mastocytosis is confined to the skin without the involvement of other tissues or organs, and is mostly found in children.
	Mastocytosis, Systemic - A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.

Mastocytosis Medical Definitions and Terms

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