Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Autocrine Motility Factor Terms and Definitions
Autocrine Motility Factor
| Medical Definition: | A member of the class of cytokines secreted by tumor cells. It elicits increases in cell motility and phosphoinositide metabolism in the secreting or producing cell via a pertussis toxin-sensitive G-protein signal transduction pathway. The factor has also been used as a marker for bladder cancer. |
| Guide Notes: | "secreted by tumor cells"; /biosyn/ drug eff /physiol /ultrastruct permitted |
| Previously Indexed: | Neoplasm Proteins (1966-1991),Tumor Markers, Biological (1988-1991) |
Autocrine Motility Factor Medical Definitions and Terms
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