Canadian Medical Guide > Chemicals and Drugs > Polycyclic Hydrocarbons > Polycyclic Hydrocarbons, Aromatic > Naphthacenes > Anthracyclines Terms and Definitions

Anthracyclines

Medical Definition:

Organic compounds that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.

Anthracyclines Categories.

	Aclarubicin - An anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity.
	Daunorubicin - A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.
	Plicamycin - A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.

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