Canadian Medical Guide > Biological Sciences > Genetic Phenomena > Variation (Genetics) > Mutation > Base Pair Mismatch Terms and Definitions




Base Pair Mismatch

Medical Definition: The presence of an uncomplementary base in double-stranded DNA caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).

Base Pair Mismatch Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

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