Canadian Medical Guide > Diseases > Musculoskeletal Diseases > Muscular Diseases > Isaacs Syndrome Terms and Definitions

Isaacs Syndrome

Medical Definition:	A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491)
Also Called:	Acquired Neuromyotonia
Previously Indexed:	Fasciculation (1995-1999)

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com