Canadian Medical Guide > Chemicals and Drugs > Enzymes and Coenzymes > Enzymes > Multienzyme Complexes > Phosphoenolpyruvate Sugar Phosphotransferase System Terms and Definitions

Phosphoenolpyruvate Sugar Phosphotransferase System

Medical Definition:	The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of adenylate cyclase. EC 2.7.1.-.
Guide Notes:	DF: PEPPTS
Also Called:	Phosphoenolpyruvate-Glycose Phosphotransferase System,Phosphoenolpyruvate Hexose Phosphotransferases
CAS Number:	EC 2.7.1.-
Previously Indexed:	Phosphoenolpyruvate (1972-1979),Phosphoric Acids (1968-1971),Phosphotransferases (1966-1979)

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