Canadian Medical Guide > Chemicals and Drugs > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Action > Chelating Agents Terms and Definitions
Chelating Agents
Medical Definition: | Organic chemicals that form two or more coordination bonds with a central metal ion. Heterocyclic rings are formed with the central metal atom as part of the ring. Some biological systems form metal chelates, e.g., the iron-binding porphyrin group of hemoglobin and the magnesium-binding chlorophyll of plants. (From Hawley's Condensed Chemical Dictionary, 12th ed) They are used chemically to remove ions from solutions, medicinally against microorganisms, to treat metal poisoning, and in chemotherapy protocols. |
Guide Notes: | D25-26 qualif; coord IM with specific chelating agent (IM) + metal being chelated (IM) |
Also Called: | Metal Antagonists |
Iron Chelating Agents - Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems. |
Chelating Agents Medical Definitions and Terms
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