Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Myelin Proteins Terms and Definitions




Myelin Proteins

Medical Definition: Proteins found in the myelin sheath. The major proteins of central nervous system myelin include: MYELIN PROTEOLIPID PROTEIN; MYELIN BASIC PROTEINS; and MYELIN-ASSOCIATED GLYCOPROTEIN. The major proteins of peripheral nervous system myelin include: MYELIN BASIC PROTEINS (myelin P1 protein and MYELIN P2 PROTEIN); MYELIN P0 PROTEIN; and MYELIN-ASSOCIATED GLYCOPROTEIN.
Guide Notes: GEN or unspecified; prefer specifics; not a synonym for MYELIN see MYELIN SHEATH; do not routinely coord with MYELIN SHEATH unless this is particularly discussed; /biosyn /drug eff /physiol /ultrastruct permitted
Previously Indexed: Myelin Sheath (1966-1976),Nerve Tissue Proteins (1966-1976)
Myelin Proteins Categories.
Canadian Medical Guide Definition Myelin Basic Proteins - A group of 7 proteins produced from a single gene by alternate splicing found in central and peripheral nervous system myelin. The major basic protein (MBP) has long been of interest because it is the antigen, that, when injected into an animal, elicits a cellular immune response that produces the CNS autoimmune disease called experimental allergic encephalomyelitis (ENCEPHALOMYELITIS, ALLERGIC). In the peripheral nervous system, myelin basic protein 18.5 kD is often referred to as the P1 protein. (From Siegel et al., Basic Neurochemistry, 5th ed, p130, 133)

Myelin Proteins Medical Definitions and Terms

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