Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Connexins Terms and Definitions




Connexins

Medical Definition: A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
Guide Notes: membrane proteins forming intermembrane channels of gap junctions
Previously Indexed: Membrane Proteins (1981-1993)
Connexins Categories.
Canadian Medical Guide Definition Connexin 43 - A 43 kD peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.

Connexins Medical Definitions and Terms

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