Canadian Medical Guide > Anatomy > Cells > Connective Tissue Cells > Macrophages > Giant Cells, Langhans Terms and Definitions
Giant Cells, Langhans
| Medical Definition: | Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity. |
| Guide Notes: | a type of macrophage; do not confuse with LANGERHANS CELLS (cutaneous) nor with ISLETS OF LANGERHANS (pancreatic); A 11 qualif |
| Previously Indexed: | Granuloma, Giant Cell (1977-1989),Macrophages (1966-1989) |
Giant Cells, Langhans Medical Definitions and Terms
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