Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Lactones > Spironolactone Terms and Definitions




Spironolactone

Medical Definition: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
Also Called: Spirolang,Aldactone,Aldactone A,SC-9420
CAS Type 1 Name: CAS Number: 52-01-7

Spironolactone Medical Definitions and Terms

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