Canadian Medical Guide > Chemicals and Drugs > Chemical Actions and Uses > Specialty Uses of Chemicals > Laboratory Chemicals > Indicators and Reagents Terms and Definitions




Indicators and Reagents

Medical Definition: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Guide Notes: NIM; coord with specific substance (IM or NIM); D25-26 qualif except /diag use; REAGENT KITS, DIAGNOSTIC & REAGENT STRIPS are also available; DF: INDICATORS
Also Called: Indicators,Reagents
Indicators and Reagents Categories.
Canadian Medical Guide Definition Affinity Labels - Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
Canadian Medical Guide Definition Chromogenic Compounds - Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).
Canadian Medical Guide Definition Cross-Linking Reagents - Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
Canadian Medical Guide Definition Intercalating Agents - Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.
Canadian Medical Guide Definition Radiopharmaceuticals - Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
Canadian Medical Guide Definition Reagent Kits, Diagnostic - Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.
Canadian Medical Guide Definition Reducing Agents - Materials that add an electron to an element or compound, that is, decrease the positiveness of its valence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Canadian Medical Guide Definition Sulfhydryl Reagents - Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling.

Indicators and Reagents Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com





Wildlife On Video »

Canadian Medical Guide Canada's Great Outdoors
Tour Canadian Rockies »
Book Banff »
Book Jasper »
Maligne Lake Boat Cruise »
Gondola Banff »
Hike Jasper »
Jasper Columbia Icefield »