Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 2-Ring > Isoquinolines > Debrisoquin Terms and Definitions




Debrisoquin

Medical Definition: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Also Called: Tendor
CAS Type 1 Name: CAS Number: 1131-64-2
Previously Indexed: Antihypertensive Agents (1966-1972),Isoquinolines (1969-1972)

Debrisoquin Medical Definitions and Terms

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