Canadian Medical Guide > Biological Sciences > Biological Phenomena, Cell Phenomena, and Immunity > Immunity > Antigen-Antibody Reactions Terms and Definitions

Antigen-Antibody Reactions

Medical Definition:

Antigen-Antibody Reactions Categories.

	Agglutination
	Antibody Affinity - A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
	Antigenic Modulation - Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.
	Cross Reactions - Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.

Antigen-Antibody Reactions Medical Definitions and Terms

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