Canadian Medical Guide > Diseases > Immunologic Diseases > Hypersensitivity > Immune Complex Diseases Terms and Definitions




Immune Complex Diseases

Medical Definition: Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other systemic immunologic diseases including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
Guide Notes: dis caused by deposition of antigen-antibody complexes with resultant damage to tissue; "immune complex" = IMMUNE COMPLEX see ANTIGEN-ANTIBODY COMPLEX
Previously Indexed: Immunologic Diseases (1971)
Immune Complex Diseases Categories.
Canadian Medical Guide Definition Arthus Reaction - A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.

Immune Complex Diseases Medical Definitions and Terms

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