Canadian Medical Guide > Chemicals and Drugs > Enzymes and Coenzymes > Enzymes > Hydrolases > Complement Activating Enzymes Terms and Definitions

Complement Activating Enzymes

Medical Definition:	Enzymes present in the complement system which activate one or more components in the system.
CAS Number:	EC 3.-
Previously Indexed:	Complement (1968-1977),Esterases (1966-1977),Hydrolases (1966-1977),Serum Globulins (1970-1977),specific complement (1975-1977)

Complement Activating Enzymes Categories.

	Complement 1r - Subcomponent of complement 1 which, when activated by C1q, activates subcomponent C1s by proteolytic cleavage.
	Complement 1s - The activated form of complement 1 which has hydrolase activity. In the classical pathway, it splits first C4 and then C2 into active components, thereby generating a new enzyme referred to as EAC142 or C42 or C3 convertase.
	Complement 3 Convertase - The enzyme which in both the classical and alternate complement pathways cleaves complement 3 into anaphylatoxin (C3a) and C3b.
	Complement Factor D - A serum protein which during the alternate pathway of complement activation converts the inactive factor B to COMPLEMENT 3 CONVERTASE. EC 3.4.21.46.

Complement Activating Enzymes Medical Definitions and Terms

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