Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 3-Ring > Dactinomycin Terms and Definitions




Dactinomycin

Medical Definition: A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
Also Called: Actinomycin,Cosmegen
CAS Type 1 Name: CAS Number: 50-76-0

Dactinomycin Medical Definitions and Terms

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