Canadian Medical Guide > Diseases > Neoplasms > Hamartoma > Proteus Syndrome Terms and Definitions

Proteus Syndrome

Medical Definition:	Hamartoneoplastic malformation syndrome of uncertain etiology characterized by partial gigantism of the hands and/or feet, asymmetry of the limbs, plantar hyperplasia, hemangiomas, lipomas, lymphangiomas, epidermal nevi, macrocephaly, cranial hyperostoses, and long-bone overgrowth. Joseph Merrick, the so-called "elephant man", apparently suffered from Proteus syndrome and not neurofibromatosis, a disorder with similar characteristics.
Guide Notes:	hamartomas & multiple abnorm; "Proteus" refers to the sea god in Greek mythol who could assume many forms; do not use /congen & do not coord with INFANT, NEWBORN, DISEASES
Previously Indexed:	Abnormalities, Multiple (1979-1991),Neoplasms, Multiple Primary (1986-1991),Neurofibromatosis 1 (1979-1990)

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