Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Germ Cell and Embryonal > Germinoma > Seminoma Terms and Definitions

Seminoma

Medical Definition:	A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)
Guide Notes:	/blood supply /chem /second /secret /ultrastruct permitted; coord IM with TESTICULAR NEOPLASMS (IM)
Previously Indexed:	Dysgerminoma (1966-1993)

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