Canadian Medical Guide > Analytical, Diagnostic and Therapeutic Techniques and Equipment > Investigative Techniques > Genetic Techniques > DNA Footprinting Terms and Definitions




DNA Footprinting

Medical Definition: A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Guide Notes: DNA FINGERPRINTING is available
Also Called: Footprints, DNA

DNA Footprinting Medical Definitions and Terms

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