Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Amines > Ethylamines > Phenethylamines Terms and Definitions
Phenethylamines
Medical Definition: | A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed) |
Amphetamines - Analogs or derivatives of AMPHETAMINE. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopression, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation. | |
Dexfenfluramine - The S-isomer of FENFLURAMINE. It is a serotonin agonist and is used as an anorectic. Unlike fenfluramine, it does not possess any catecholamine agonist activity. | |
Dimethoxyphenylethylamine | |
Fendiline - Coronary vasodilator; inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as antiarrhythmic and antianginal agents. | |
Fenfluramine - A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release. | |
Hexoprenaline - Stimulant of adrenergic beta 2 receptors. It is used as a bronchodilator, antiasthmatic agent, and tocolytic agent. | |
Mescaline - Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church. | |
p-Methoxy-N-methylphenethylamine - A potent mast cell degranulator. It is involved in histamine release. | |
Prenylamine - A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406) | |
Selegiline - A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. | |
Verapamil - A calcium channel blocker that is a class IV anti-arrhythmia agent. |
Phenethylamines Medical Definitions and Terms
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