Canadian Medical Guide > Chemicals and Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormone Antagonists > Estrogen Receptor Modulators > Selective Estrogen Receptor Modulators Terms and Definitions

Selective Estrogen Receptor Modulators

Medical Definition:	A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate the estrogen receptor, but act as either an estrogen agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
Guide Notes:	do not confuse with ESTROGEN RECEPTOR MODULATORS
Previously Indexed:	Receptors, Estrogen (1996-1999)

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com