Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Alkaloids > Ergot Alkaloids > Ergotamines Terms and Definitions

Ergotamines

Medical Definition:	A series of structurally-related alkaloids containing the ergotaman backbone structure.
Previously Indexed:	Ergolines (1969-1974),Ergotamine (1966-1974)

Ergotamines Categories.

	Bromocriptine - A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.
	Dihydroergocornine - A 9,10alpha-dihydro derivative of ERGOTAMINE that contains isopropyl sidechains at the 2' and 5' positions of the molecule.
	Dihydroergocristine - A 9,10alpha-dihydro derivative of ERGOTAMINE that contains an isopropyl sidechain at the 2' position of the molecule.
	Dihydroergocryptine - A 9,10alpha-dihydro derivative of ERGOTAMINE that contains an isopropyl sidechain at the 2' position and an alpha-isobutyl sidechain at 5'alpha position of the molecule.
	Dihydroergotamine - A 9,10alpha-dihydro derivative of ERGOTAMINE. It is used as a vasoconstrictor, specifically for the therapy of migraine.
	Dihydroergotoxine - A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE, DIHYDROERGOCRISTINE, and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
	Ergotamine - A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of MIGRAINE.

Ergotamines Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com

Wildlife On Video »

Canada's Great Outdoors
Tour Canadian Rockies »
Book Banff »
Book Jasper »
Maligne Lake Boat Cruise »
Banff Gondola »
Hike Jasper »
Jasper Columbia Icefield »
Hike Johnston Canyon »
Golden Skybridge »
Lake Minnewanka Boat Cruise »
Columbia Icefields Skywalk »