Canadian Medical Guide > Chemicals and Drugs > Enzymes and Coenzymes > Enzyme Precursors > Plasminogen Terms and Definitions




Plasminogen

Medical Definition: Precursor of fibrinolysin (plasmin). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
Guide Notes: an enzyme precursor & fibrinolytic agent; /antag: do not confuse with PLASMINOGEN INACTIVATORS which modulate PLASMINOGEN ACTIVATORS, not PLASMINOGEN
Also Called: Glu-Plasminogen
CAS Type 1 Name: CAS Number: 9001-91-6
Plasminogen Categories.
Canadian Medical Guide Definition Angiostatins - Circulating 38 kD proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.

Plasminogen Medical Definitions and Terms

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